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<p>新学术领域“分子机器人学”<br>计测自動制御学会（SICE）系统信息部门 调查研究会“分子机器人研究会”</p>
<p>我们将举办专题讲座，邀请以 DNA 水凝胶研究著称的康奈尔大学 Dan Luo 教授莅临主讲。</p>
<p>“DNA as an innovative nano-material” Dan Luo 教授 / 康奈尔大学</p>

<dl>
  <dt>时间</dt>
  <dd>2013年7月6日（周六）15:00–16:30</dd>

  <dt>地点</dt>
  <dd>新学术领域“分子机器人学”田町办公室　CIC Tokyo 5层 Open Space</dd>

  <dt>交通/访问</dt>
  <dd>http://www.cictokyo.jp/</dd>

  <dt>联系方式</dt>
  <dd>村田 智（东北大学） 该邮件地址已受到反垃圾邮件插件保护。要显示它需要在浏览器中启用 JavaScript。</dd>
</dl>

<p>欢迎任何人参加，敬请踊跃报名参加。</p>

<p>————————————————————————</p>

<p>“DNA as an innovative nano-material”</p>
<p>Dan Luo<br>Departments of Biological and Environmental Engineering, Cornell<br>University, Ithaca, New York, 14853 USA. E-mail: 该邮件地址已受到反垃圾邮件插件保护。要显示它需要在浏览器中启用 JavaScript。</p>

<p>摘要<br>Although our group has not worked on robotics per se, we have been<br>focusing on engineering DNA as a true polymer, which might provide<br>unique molecular tools and unprecedented materials for molecular<br>robotics. Inspired by polymers’ topologies and combined with molecular<br>biology’s tool kits, previously we have engineered DNA as a<br>nanomaterial into different topological forms including Y-shaped DNA,<br>dendrimer-like DNA, and networked DNA. From these DNA nanostructures,<br>we have created DNA nanobarcodes, DNA hydrogels, DNA liposomes<br>(DNAsomes), and DNA-organized nanoparticles. Many of these DNA-based<br>materials can be used as molecular sensing tools as well as molecular<br>delivery vehicles for cargos (including genes, siRNA, proteins, etc).<br>Recently we have also created a DNA hydrogel that can produce large<br>amounts of functional proteins without any living cells (termed<br>P-gel). Based on P-gel, we have further created functional<br>“quasi-cells” — compartmentalized structures that can be used to<br>mimic cells for protein production, engineering, and delivery. Most<br>recently, we have created a mechanical metamaterial that is based<br>entirely on DNA molecules. This metamaterial has both liquid and solid<br>properties and can return to its original shape even after unlimited<br>amorphous transitions. We believe that our DNA-based bulk materials<br>can be an invaluable tools and materials for the molecular robotics<br>field, and we are eager to collaborate.</p>

<p>代表性参考文献：<br>
1. Nature Nanotech. 7, 816-820 (2012)<br>
2. Nature Communication 2, 587-590 (2011)<br>
3. Nature Nanotech. 6, 268-276 (2011)<br>
4. Nature Protocols 4, 1759-1770 (2009)<br>
5. Nature Nanotech. 4, 430-436 (2009)<br>
6. Nature Materials (Article) 8, 519-527 (2009)<br>
7. Nature Materials (Article) 8, 432-437 (2009)<br>
8. Nature Nanotech. (Article) 3, 693-696 (2008)<br>
9. Nature Materials 5, 797-801 (2006)<br>
10. Nature Protocols 1, 995-1000 (2006)<br>
11. Nature Biotechnology 23, 885-889 (2005)<br>
12. Nature Materials 3, 38-42 (2004)<br>
13. Nature Biotechnology 18, 893-895 (2000)<br>
14. Nature Biotechnology 18, 33-37 (2000)</p>